Table 2.
MARKERS | METHOD | COMMENTS |
---|---|---|
CD34 and vimentin | Immunostaining | Helps in diagnosis of DFSP |
CD117 | Immunostaining | Used only for GIST susceptibility to imatinib |
Apoplipoprotein B | Immunostaining | New marker for diagnosis of DFSP |
COL1A1-PDGFβ | FISH | Confirms probable susceptibility to imatinib; diagnosis of DFSP if loss of CD34 observed |
t(17;22) | RT-PCR | Confirms probable susceptibility to imatinib; diagnosis of DFSP if loss of CD34 observed |