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. Author manuscript; available in PMC: 2012 Feb 25.
Published in final edited form as: Immunity. 2011 Feb 25;34(2):163–174. doi: 10.1016/j.immuni.2011.02.003

Figure 3.

Figure 3

Increased recovery of aberrant Vβ14-Dβ1 signal joints from mice expressing RAG-2(T490A) or deficient in Skp2. Top, Vβ14 and Dβ1 RSSs and flanking coding sequences. Heptamer and nonomer elements are indicated in boldface; coding sequences are underlined and capitalized. In each sequence below, the RSSs are in lowercase and insertions in uppercase. Sets of sequences from RAG-2 wild-type, RAG-2(T490A), Skp2+/− and Skp2−/− animals are indicated. Nucleotide additions of more than three contiguous bases identical to either coding flank are capitalized in blue. The sizes of deletions from each signal end, in bp, are given in parentheses. Potential microhomologies are indicated in red type. The number of junctions obtained for a given sequence is indicated at right.