Table 2.
Univariate analysis of prognostic factors related to axillary lymph node invasion
| Factor | Variable | No. of women | Positive nodes (%) | Odds ratio | 95% CI | P |
| Histology | Ductal | 45 | 29 (64%) | 1.00 | ||
| Other | 7 | 6 (86%) | 3.31 | 0.37-29.97 | 0.287 | |
| Tumor mass | Single | 36 | 21 (58%) | 1.00 | ||
| Other | 16 | 14 (88%) | 5.00 | 0.99-25.34 | 0.052 | |
| Clinical response | No | 13 | (77%) | 1.00 | ||
| Yes | 39 | 25 (64%) | 0.54 | 0.13-2.28 | 0.398 | |
| ER | Negative | 22 | 16 (73%) | 1.00 | ||
| Positive | 30 | 19 (63%) | 0.65 | 0.20-2.14 | 0.477 | |
| PR | Negative | 28 | 21 (75%) | 1.00 | ||
| Positive | 24 | 14 (58%) | 0.47 | 0.14-1.52 | 0.205 | |
| c-erb-B2 | Negative | 37 | 24 (64%) | 1.00 | ||
| Positive | 15 | 11 (73%) | 1.49 | 0.37-5.62 | 0.557 | |
| 53 | Negative | 34 | 24 (71%) | 1.00 | ||
| Positive | 18 | 11 (61%) | 0.65 | 0.20-2.18 | 0.489 | |
| Ki67 | <20% | 17 | 6 (35%) | 1.00 | ||
| ≥ 20% | 33 | 27 (82%) | 8.25 | 2.18-31.23 | 0.002 | |
| MDR1 (IHC) | Negative | 14 | 8 (57%) | 1.00 | ||
| Positive | 9 | 7 (78%) | 2.63 | 0.39-17.46 | 0.318 | |
| LRP | Negative | 8 | 3 (38%) | 1.00 | ||
| Positive | 23 | 17 (74%) | 4.72 | 0.86-26.04 | 0.075 | |
| MDR1 (RT-PCR) | Negative | 24 | 13 (54%) | 1.00 | ||
| Positive | 22 | 18 (82%) | 3.81 | 0.99-14.67 | 0.052 | |
| MDR1 (RT-PCR) | Both negative | 8 | 3 (38%) | 1.00 | ||
| and LRP combined | ||||||
| LRP+ MDR1- | 7 | 4 (57%) | 2.22 | 0.28-17.63 | 0.450 | |
| Both positive | 15 | 13 (87%) | 10.83 | 1.37-85.43 | 0.024 |
CI, confidence interval; ER, estrogen receptor; PR, progesterone receptor; RT-PCR, reverse-transcriptase-mediated polymerase chain reaction.