TABLE 2.

Fluctuation behavior at mutation-rate equilibrium

f	Q	tlet	Umina	Umedb	Tcorr × 10−6c	Twait × 10−6d	× 106e
1.1	0.5	0	0.038 (0.017)	0.033	0.13	0.78 (12)	7.86
1.1	0.5	0.01	0.032 (0.016)	0.027	0.22	1.09 (22)	6.55
1.1	0.5	0.1	0.026 (0.010)	0.025	0.16	1.80 (10)	3.16
1.3	0.1	0	0.065 (0.031)	0.055	0.11	0.59 (37)	31.9
1.3	0.1	0.1	0.048 (0.024)	0.042	0.13	0.88 (21)	15.8
1.3	0.2	0	0.022 (0.010)	0.019	0.09	0.61 (41)	2.62
1.3	0.2	0.1	0.020 (0.008)	0.019	0.08	1.00 (22)	1.99
1.3	0.5	0	0.0048 (0.003)	0.004	0.25	0.86 (37)	0.18
1.3	0.5	0.1	0.0052 (0.003)	0.005	0.30	1.18 (16)	0.20
1.5	0.01	0.1	0.088 (0.057)	0.056	1.98	8.73 (1)	69.4
1.5	0.02	0	0.072 (0.043)	0.056	0.29	2.53 (4)	50.7
1.5	0.02	0.01	0.065 (0.039)	0.056	0.36	1.91 (3)	41.0
1.5	0.02	0.01	0.072 (0.041)	0.084	0.37	3.35 (2)	45.8
1.5	0.02	0.1	0.052 (0.020)	0.056	0.45	4.85 (3)	17.0
1.5	0.05	0.1	0.029 (0.012)	0.025	0.26	2.27 (11)	4.13
2	10−3	0	0.025 (—)	0.025	—	— (0)	2.45

Parameter values: N = 500, = 0.1, t_mut = 0.01, U₀ = 0.025.

^aTime average of the minimal mutation rate in the population and its standard deviation.

^bMedian of the minimal mutation rate in the population.

^cCorrelation time of fluctuations in U.

^dMean waiting time for a fluctuation of U that is twice its median and within parentheses the number of such fluctuations.

^eAverage of the fitness loss rate from the slope of the linear regression of −ln(fitness) vs. time.