TABLE 1.

Mutation and selection parameters fitted in the model and limits for uniform priors

Parameter	Meaning	Limits of uniform prior
knCG	Mutation rate at non-CpG sitesa	0, 0.4
α	CpG:non-CpG mutation rate ratio	2, 20
βnCG	Transition:transversion ratio at non-CpG sites	1, 5
βCG	Transition:transversion ratio at CpG sites	1, 20
CN	Constraint at nonsynonymous sites	−1, 1
CS	Constraint at synonymous sites	−1, 1

^aThe mutation rate refers to the rate down one of the two lineages.