Table.
Genotypes of Progeny From Heterozygous Intercrosses
| β8 integrin genotypes |
|||||
|---|---|---|---|---|---|
| Intercrosses | +/+ | +/− | −/− | Expected viable −/− | P value |
| Outbred embryos | |||||
| E14.5-16.5 | 5 | 13 | 1 | 6 | |
| E17.5 | 12 | 22 | 7 | 11 | |
| E18.5 | 8 | 21 | 4 | 10 | |
| Total | 25 (27) | 56 (60) | 12 (13) | 27 | 0.09 |
| P14-P21 | |||||
| Outbred | 196 (35) | 353 (63) | 14 (2) | 183 | <0.0001 |
| Congenic | 168 (38) | 267 (61) | 6 (1) | 145 | <0.0001 |
Data are presented as total number of progeny with percentages in parentheses. Expected viable is calculated with the assumption that the sum of (+/+) and (+/−) equals 75%. A Chi-square test was used to determine statistical significance.
E, embryonic day; P, postnatal day.