Table 1.
Correlation Between FoxM1 IHC Status and Clinicopathological Parameters in Colorectal Carcinoma
| Total |
High expression |
Low expression |
|||||
|---|---|---|---|---|---|---|---|
| No. | % | No. | % | No. | % | P value | |
| Sample size | n = 370 | n = 245 | 66.2 | n = 125 | 33.8 | ||
| Age | |||||||
| ≤0 years | 122 | 33.0 | 85 | 69.7 | 37 | 30.3 | 0.3219 |
| >50 years | 248 | 67.0 | 160 | 64.5 | 88 | 33.8 | |
| Sex | |||||||
| Male | 175 | 47.3 | 121 | 69.1 | 54 | 30.9 | 0.2590 |
| Female | 195 | 52.7 | 124 | 63.6 | 71 | 36.4 | |
| Tumor site | |||||||
| Left colon | 306 | 82.7 | 197 | 64.4 | 109 | 35.6 | 0.0954 |
| Right colon | 64 | 17.3 | 48 | 75.0 | 16 | 25.0 | |
| Histological type | |||||||
| Adenocarcinoma | 323 | 87.3 | 210 | 65.0 | 113 | 35.0 | 0.1914 |
| Mucinous carcinoma | 47 | 12.7 | 35 | 74.5 | 12 | 25.5 | |
| Tumor stage | |||||||
| I | 50 | 14.2 | 33 | 66.0 | 17 | 34.0 | 0.4073 |
| II | 120 | 34.1 | 74 | 61.7 | 46 | 38.3 | |
| III | 138 | 39.2 | 94 | 68.1 | 44 | 31.9 | |
| IV | 44 | 12.5 | 33 | 75.0 | 11 | 25.0 | |
| Differentiation | |||||||
| Well | 29 | 7.8 | 22 | 75.9 | 7 | 24.1 | 0.0200 |
| Moderate | 276 | 74.6 | 172 | 62.3 | 104 | 37.7 | |
| Poor | 65 | 17.6 | 51 | 78.5 | 14 | 21.5 | |
| Ki67⁎ | |||||||
| ≥50 | 304 | 86.4 | 211 | 69.4 | 93 | 30.6 | 0.0018 |
| <50 | 48 | 13.6 | 22 | 45.8 | 26 | 54.2 | |
| MMP-9 | |||||||
| >100 | 241 | 67.7 | 176 | 73.0 | 65 | 27.0 | 0.0002 |
| ≤100 | 115 | 32.3 | 61 | 53.0 | 54 | 47.0 | |
| Overall survival | |||||||
| 5 Years | 62.8 | 69.0 | 0.4543 | ||||
⁎
Analysis failure of some spots for these IHC markers was attributed to missing or nonrepresentative spots.