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FAP Expression in Fibroblasts in Different Colorectal Lesions
| FAP negative | FAP positive |
|||
|---|---|---|---|---|
| + | ++ | +++ | ||
| Normal mucosa | 12 | 0 | 0 | 0 |
| Normal mucosa adjacent to CRC | 12 | 0 | 0 | 0 |
| Hyperplastic polyps | 16 | 0 | 0 | 0 |
| Tubular adenomas | 30 | 0 | 0 | 0 |
| Villous adenomas | 15 | 0 | 0 | 0 |
| Tubulovillous adenomas | 10 | 0 | 0 | 0 |
| Adenoma adjacent to CRC | 19 | 0 | 0 | 0 |
| Colorectal cancer | 0 | 15 | 19 | 27 |
+, weak; ++, moderate; +++, strong FAP staining; CRC, colorectal cancer; FAP, fibroblast activation protein.
