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Cdc42DN abrogated the promoting effect of FGD1 on osteogenesis. A: hMSCs were infected with FGD1wt alone or coinfected with FGD1wt and Cdc42DN and grown in growth medium for 14 days. Cells were fixed and stained for alkaline phosphatase activity. Scale bar = 100 μm. Result was quantified in B. Data are represented as mean ± SD, n = 3. *P < 0.05 (by Student's t-test).
