Table 4.
Association of AR associated haplotypes in UGRP1 gene
| Haplotype | rs7726552 | rs7727031 | UGRP1-G-1351A | rs6882292 | rs17107353 | rs17703574 | UGRP1-C1360A | Haplotype frequency | P value* | |
|---|---|---|---|---|---|---|---|---|---|---|
| 717 controls | 795 cases | |||||||||
| H1 | A | C | G | A | A | G | C | 0.053 | 0.059 | 0.536 |
| H2 | A | T | G | G | T | G | C | 0.696 | 0.655 | 0.017 |
| H3 | A | T | A | G | T | G | A | 0.071 | 0.066 | 0.637 |
| H4 | T | T | G | G | T | G | C | 0.135 | 0.162 | 0.036 |
| H5 | A | T | G | G | A | T | C | 0.046 | 0.058 | 0.120 |
Haplotypes are constructed using the sliding window method by PLINK software. Haplotype frequencies are estimated using the Haploview software.
* P value calculated using χ2 test of association for haplotypes.