Table1.
The characteristics of various phenotypes of PCOS using Rotterdam criteria
| Phenotype characteristic | Group 1 (n = 66) ANOVU+ HA ± PCO | Group2 (n = 43) HA + PCO | Group3 (n = 27) ANOVU + PCO | Normal (n = 423) |
|---|---|---|---|---|
| Age (years) | 31.0 (25.8-37.3)* | 30.0 (25.0-40.0)* | 35.0 (28.0-39.0) | 36.0 (30.0-41.0) |
| BMI (kg/m2) | 27.0 (25.8-37.3) | 25.0 (21.6-29.2) | 25.6 (23.0-31.2) | 26.4 (23.1-29.4) |
| WHR | 0.81 (0.76-0.85) | 0.78 (0.75-0.85) | 0.83 (0.78-0.86) | 0.81 (0.76-0.85) |
| Systolic Blood Pressure (mm/Hg) | 110.0 (100.0-120.0) | 100.0 (105.0-110.0) | 110.0 (100.0-110.0) | 110.0 (100.0-120.0) |
| Diastolic Blood Pressure (mm/Hg) | 70.0 (60.0-80.0) | 70.0 (60.0-70.0) | 70.0 (60.0-70.0) | 70.0 (60.0-80.0) |
| % Women with history of Primarily infertility | 27.3* | 21.6* | 31.0* | 10.6 |
| % women with family history of HA | 42.4* | 20.9 | 11.1 | 14.0 |
| % women with family history of ANOVU | 36.4*†‡ | 14.0 | 22.2 | 19.0 |
| LH/FSH Ratio | 0.77 (0.46-1.04) | 0.64 (0.45-1.0) | 0.69 (0.5-1.1) | 0.6 (0.43-0.86) |
| Total T (ng/ml) | 0.75 (0.57-0.88) *‡ | 0.81 (0.52-0.93) *†† | 0.41 (0.29-0.53) | 0.51 (0.32-0.68) |
| FAI | 4.7 (3.1-6.9) *‡ | 4.9 (3.6-7.1) *†† | 2.2 (1.3-2.8) | 2.6 (1.5-3.7) |
| A4 (ng/ml) | 5.8 (5.1-6.9) *‡ | 2.1 (1.8-2.5) *†† | 1.1 (0.9-2.0) | 1.1 (0.9-1.7) |
| DHEAS (μg/Dl) | 196.1 (149.5-238.1) *‡ | 200.5 (138.9-248.0) *†† | 141.5 (45.7-186.7) | 138.0 (58.3-192.8) |
| SHBG (nmol/L) | 54.8 (42.7-70.7) * | 54.4 (45.0- 67.1) * | 62.6 (49.1-88.1) | 67.2 (53.4-92.4) |
Values are given as median (Inter quartile range), +The hormonal and biochemical assessments of those women who use insulin sensitizers and/or oral contraceptive pills were not included for statistical analysis. * = versus normal group, p < 0.008, † = Group1 versus Group2, P < 0.008; ‡ = Group 1 versus Group 3; † † = Group2 versus Group3, p < 0.008; WHR, waist to hip ratio; Normal group, eumenorrheic and without HA and PCO; ANOVU, oligo/anovulation; HA, hyperandrogenemia and/or hyperandrogenism; PCO,polycystic ovaries; DHEAS, Dehydroepiandrosterone sulfate; Total T, Total testosterone; A4, Androstendion; SHBG, Sex Hormone Binding Globulin; FAI, Free androgen index.