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Morphologic and immunophenotypic squamous differentiation correlates with increased acetylation of TC-797 xenografts treated with HDACi (LBH-589). AcL, immunohistochemistry using anti-acetyl-lysine antibody (Cell Signaling Technologies); Veh1, vehicle control (DMSO) treated mouse 1; Veh2, vehicle treated mouse 2; LBH1, LBH-589 treated test mouse 1; LBH2, LBH-589 treated test mouse 2. Magnification (scale bar, 25um) is identical for all panels.
