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. Author manuscript; available in PMC: 2012 May 1.

Published in final edited form as: Free Radic Biol Med. 2011 Jan 21;50(9):1065–1074. doi: 10.1016/j.freeradbiomed.2011.01.016

Table 1.

Carotid Artery Injury Model Morphometric Analysis in Hormonally Intact Rats

	Males		Females
	Injury	Injury + PROLI/NO 26 mg/kg	Injury	Injury + PROLI/NO 26 mg/kg	Injury + PROLI/NO 39 mg/kg
Weight (grams)	371 ± 3	374 ± 4	269 ± 14 ^b	239 ± 7 ^c	257 ± 3 ^c
Circumference	1.71 ± 0.02	1.60 ± 0.02	1.44 ± 0.03 ^b	1.37 ± 0.02 ^c	1.41 ± 0.01 ^c
Luminal Area	8.33 ± 0.14	8.35 ± 0.20	5.82 ± 0.29 ^b	7.63 ± 0.17 ^a,^c	7.90 ± 0.17*
Intima Area	21.96 ± 1.15	7.79 ± 0.44^a	19.12 ± 0.97	9.76 ± 0.71 ^a	6.10 ± 0.23 ^a
Media Area	20.29 ± 0.80	14.69 ± 0.47^a	18.00 ± 0.38	12.89 ± 0.37 ^a	12.37 ± 0.31 ^a
Intima/Media	1.18 ± 0.08	0.53 ± 0.03^a	1.06 ± 0.06	0.73 ± 0.05 ^a	0.51 ± 0.02 ^a
Intima/(Intima + Media)	0.53 ± 0.01	0.35 ± 0.01^a	0.51 ± 0.01	0.41 ± 0.02 ^a,^c	0.33 ± 0.01 ^a

^a

P < 0.05 compared to same sex injury.

^b

P < 0.05 compared to male injury-alone.

^c

P < 0.05 compared to male injury + NO. n=6 per treatment group. All measured units of the artery are arbitrary units from ImageJ