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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Free Radic Biol Med. 2011 Jan 21;50(9):1065–1074. doi: 10.1016/j.freeradbiomed.2011.01.016

Table 2.

Carotid Artery Injury Model Morphometric Analysis in Hormonally Castrated Rats

Males
 Females
Injury Injury +
PROLI/NO 26
mg/kg		 Injury Injury +
PROLI/NO 26
mg/kg		 Injury +
PROLI/NO 39
mg/kg
Weight (grams) 347 ± 5 357 ± 4 285 ± 5 b 243 ± 7 c 271 ± 6 c



Circumference 		1.61 ±
0.0
1		 1.56 ± 0.02 1.50 ±
0.
0
2
b 		1.51 ± 0.02 1.42 ± 0.02 c


Luminal Area 		8.42 ±
0.1
4		 8.86 ± 0.23 8.02 ±
0.
2
4		 7.97 ± 0.19 c 7.89 ± 0.24 c



Intima Area 		17.6 ±
0.9
2		 7.3 ± 0.25 a 13.0 ±
0.
6
8
b 		8.5 ± 0.27 a 4.4 ± 0.39 a,c


Media Area 		17.6 ±
0.6
1		 12.3 ± 0.43 a 17.7 ±
0.
8
1		 14.6 ± 0.33 10.8 ± 0.38 a



Intima/Media 		1.00 ±
0.0
5		 0.61 ± 0.02 a 0.71 ±
0.
0
4
b 		0.61 ± 0.02 0.41 ± 0.03 a,c

Intima/(Intima +
Media) 		0.50 ±
0.0
1		 0.37 ± 0.01 a 0.44 ±
0.
0
b 		0.38 ± 0.01 0.27 ± 0.02 a,c
a

P < 0.05 compared to same sex injury.

b

P < 0.05 compared to male injury alone.

c

P < 0.05 compared to male injury + NO. n=6 per treatment group. All measured units of the artery are arbitrary units from ImageJ