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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Cancer Res. 2011 Feb 7;71(7):2488–2496. doi: 10.1158/0008-5472.CAN-10-2820

Figure 1. Local Radiation Therapy increases tumor infiltration by innate immune cells.

Figure 1

a) Flow cytometric analysis of CD45+ hematopoietic cells infiltrating untreated B16F1 tumors or tumors treated with 25 Gy local RT at 3 and 5 days post-RT. b) Surface staining of infiltrating CD45+ cells for the myeloid marker CD11b and DC marker CD11c. Gated percentages represent the proportion of CD11b+CD11c+ cells in the parental CD45+ gate (shown in a). c) Bar graph of data in (a) (*p=0.0432 for No RT vs. RT D+3, p=0.0101 for No RT vs. RT D+5). d) Bar graph of the data in (b) (*p=0.0182, **p=0.0031). Values were calculated by the formula (%CD11c+ × %CD45+) for each sample individually and then averaged for the three samples in each group. Error bars represent the standard deviation among the three animals in each group (n.s. = not significant).