Figure 6.

MINK disrupts Rap2-mediated regulation of surface GluR1 clusters. A, Representative images of MINK expression effects on Rap2-mediated reduction in surface AMPA receptor clusters. B, Quantification of mean sGluR1 cluster intensity in dendritic segments cotransfected with DsRed and pGW1 empty vector, or combinations of transfections as indicated (below graph). Mean cluster integrated intensities were normalized to empty vector control. Error bars indicate ±SEM, where **p < 0.01, ***p < 0.001 is relative to empty vector, and ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 is relative to MINK cotransfected with Rap2(ca), ANOVA. n ≥ 12 neurons for each.