. Author manuscript; available in PMC: 2012 Mar 1.

Published in final edited form as: Clin Cancer Res. 2011 Jan 19;17(5):1169–1180. doi: 10.1158/1078-0432.CCR-10-2277

Table 3.

Comparison of T790M Mutation Rate by Type of Testing Method

	STANDARD SEQUENCING	FRAGMENT ANALYSIS	COMBINED STANDARD & LNA PCR/SEQUENCING
Total cases tested	69	45	64
Positive cases (rate)	34 (49%)	24 (53%)^**	45 (70%)^*
Negative cases (rate)	35 (51%)	21 (47%)	19 (30%)

p= 0.02,

^**

p=n.s. (Fisher’s Exact test for comparison to standard sequencing)