Table 2. Changes in external vascular diameter (μm) of anterior and posterior cerebral arteries: main collateral pathways after three-vessel occlusion (3-VO).

	Anterior cerebral artery		Posterior cerebral artery
	Ipsilateral	Contralateral	Ipsilateral	Contralateral
Nonischemic control	251±14	290±19	187±10	196±11
1 Week 3-VO
Vehicle (n=5)	279±14	237±9	250±11‡	199±12
Leptin (n=6)	286±12	224±12	281±11	184±9
GM-CSF (n=5)	322±12	311±15* (+31%)	317±13*	231±10

GM-CSF, granulocyte–macrophage colony stimulating factor.

After latex infusion, external diameter of main collateral pathways was determined using stereo-zoom microscopy (^‡P<0.05 compared with nonischemic control; ^*P<0.05 compared with vehicle 3-VO).