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Digital photomicrographs of IgG-stained sections used to assess the blood–brain barrier (BBB) damage in (A) a sham-operated rat and (B) a rat 2 days after focal cerebral ischemia. (C) Semiquantitative analysis of IgG immunoreactivity in the ipsilateral thalamus after cerebral ischemia. Data are expressed as mean±standard error of the mean (s.e.m.), n=4 to 6. Statistical significances; **P<0.01 (compared with sham group), #P<0.05 (compared with 3 months ischemic group). Scale bar=1 mm.
