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. Author manuscript; available in PMC: 2012 Apr 15.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Feb 15;21(8):2550–2553. doi: 10.1016/j.bmcl.2011.02.013

Figure 2.

Figure 2

Solution structure of AERP mimetic analog. The overall fold between AERP-2 and AERP-2A is similar (rmsd for back bone structure is 2.9Å) and rmsd for all non-hydrogen atoms is 5.64Å. The disposition of Arg residues in these two structures are different and the results show the effect of introducing a serine in the cyclic ring of AERP.