Table 1.
Demographic and Epidemiologic Data for 30 Patients with Confirmed Chikungunya Virus (CHIKV) Infection
| Patient (Sex, Age in years) | Duration of fever, Days | Acute illness severitya | CHIKV load, pfu/mL | CRP level, mg/dL | Lymphocytes, % | Neutrophils, % | Monocytes, % | Clinical outcomeb |
| CHIKV 1 (M, 40) | 3 | Severe | 5.62E+08 | 77.9 | 5.9 | 84.2 | 8.7 | Complete recovery |
| CHIKV 2 (M, 23) | 8 | Severe | 3.45E+08 | 93.7 | 5.8 | 84.0 | 9.6 | Complete recovery |
| CHIKV 3 (M, 62) | 7 | Severe | 3.45E+08 | 46.7 | 13.6 | 73.8 | 10.2 | Lethargy, weakness |
| CHIKV 4 (M, 43) | 5 | Severe | 3.45E+08 | 46.1 | 5.1 | 85.3 | 9.1 | Complete recovery |
| CHIKV 5 (M, 29) | 6 | Severe | 2.12E+08 | 58.9 | 6.3 | 79.4 | 14.2 | Complete recovery |
| CHIKV 6 (M, 35) | 7 | Severe | 1.14E+07 | 0.4 | 32.3 | 57.9 | 8.5 | Complete recovery |
| CHIKV 7 (M, 30) | 4 | Severe | 1.14E+07 | 29.6 | 11.5 | 77.6 | 10.6 | Complete recovery |
| CHIKV 8 (M, 35) | 4 | Severe | 2.64E+06 | 9.0 | 11.6 | 74.1 | 13.5 | Complete recovery |
| CHIKV 9 (M, 26) | 3 | Severe | 9.97E+05 | 20.8 | 4.3 | 87.7 | 7.9 | Complete recovery |
| CHIKV 10 (M, 28) | 4 | Severe | 3.76E+05 | 22.8 | 15.9 | 75.7 | 7.5 | Complete recovery |
| CHIKV 11 (M, 49) | 2 | Severe | 3.76E+05 | 25.7 | 13.3 | 74.8 | 11.6 | Complete recovery |
| CHIKV 12 (M, 50) | 6 | Severe | 2.31E+05 | 36.9 | 5.9 | 80.0 | 8.6 | Complete recovery |
| CHIKV 13 (M, 38) | 3 | Severe | 2.31E+05 | 34.2 | 30.3 | 56.9 | 12.3 | Complete recovery |
| CHIKV 14 (M, 60) | 3 | Mild | 1.42E+05 | 56.4 | 9.1 | 84.4 | 5.9 | Complete recovery |
| CHIKV 15 (F, 62) | 7 | Severe | 5.36E+04 | 8.5 | 24.3 | 91.0 | 3.0 | Complete recovery |
| CHIKV 16 (M, 45) | 0 | Mild | 5.36E+04 | 2.1 | 20 | 57.0 | 12.0 | Complete recovery |
| CHIKV 17 (M, 34) | 3 | Mild | 5.36E+04 | 9.2 | 45.4 | 51.0 | 15.9 | Complete recovery |
| CHIKV 18 (M, 29) | 2 | Severe | 2.02E+04 | 46.9 | 18.6 | 70.5 | 13.3 | Persistent arthralgia |
| CHIKV 19 (F, 67) | 7 | Mild | 2.02E+04 | 10.7 | 6 | 68.0 | 19.0 | Complete recovery |
| CHIKV 20 (M,24) | 3 | Mild | 2.02E+04 | 9.3 | 45.6 | 41.0 | 12.6 | Complete recovery |
| CHIKV 21 (M, 34) | 0 | Mild | 2.02E+04 | 1.0 | 33.8 | 41.9 | 17.4 | Complete recovery |
| CHIKV 22 (M, 28) | 7 | Mild | 1.24E+04 | 2.9 | 32.6 | 56.8 | 8.2 | Complete recovery |
| CHIKV 23 (M, 42) | 2 | Mild | 1.24E+04 | 12.4 | 24.3 | 67.0 | 7.9 | Complete recovery |
| CHIKV 24 (F, 40) | 6 | Mild | 9.37E+03 | 17.3 | 69.9 | 69.9 | 15.4 | Persistent arthralgia |
| CHIKV 25 (F, 31) | 6 | Mild | 7.64E+03 | 32.5 | 11.7 | 81.8 | 6.0 | Persistent arthralgia |
| CHIKV 26 (M, 46) | 9 | Mild | 7.64E+03 | 4.9 | 28.2 | 57.9 | 12.7 | Complete recovery |
| CHIKV 27 (M, 26) | 4 | Mild | 7.64E+03 | 7.8 | 36.1 | 37.2 | 17.3 | Persistent arthralgia |
| CHIKV 28 (M,28) | 5 | Severe | 7.64E+03 | 0.3 | 18 | 60.0 | 14.0 | Complete recovery |
| CHIKV 29 (M, 47) | 8 | Mild | 4.69E+03 | 2.0 | 28 | 49.0 | 21.0 | Complete recovery |
| CHIKV 30 (M, 39) | 1 | Mild | BDL | 1.8 | 30.2 | 49.3 | 8.5 | Complete recovery |
NOTE. BDL, below detection limit (1E + 02 pfu/mL); CRP, C-reactive protein.
All patients do not have any pre-morbid conditions.
The 4 clinical parameters, CRP level (normal range, 0.0–5.0 mg/dL), lymphocyte percentage (normal range, 20%–45%), neutrophil percentage (normal range, 45%–75%), and monocyte percentage (normal range, 3%–10%), were determined at admission to the hospital at acute phase (median, 4 days after infection onset).
a
Severity was defined as having a temperature >38.5°C, pulse rate >100 beats/min, or platelet count <100 x 109 cells/L.
b
Clinical outcome at chronic phase (2-3 months after infection onset).