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. 2011 Mar 15;203(6):780–790. doi: 10.1093/infdis/jiq118

Table 3.

The Increased Risk for Mortality Conferred by Higher sCD14 Levels Does Not Differ between Treatment Arms

Drug conservation arm
Viral suppression arm
Biomarker OR (95% CI)a P OR (95% CI) P P for interaction
sCD14 level, ×106 pg/mL 3.5 (1.5–8.3) .004 2.0 (0.8–5.4) .15 .43
LPS, pg/mL 1.0 (0.6–1.7) .96 0.7 (0.3–1.7) .40 .63
I-FABP, pg/mL 0.9 (0.4–2.1) .84 2.3 (0.6–8.8) .19 .58
16S rDNA, copies/μL 0.9 (0.4–2.2) .90 0.5 (0.2–1.4) .21 .26
EndoCAb, MMU/mL 1.1 (0.8–1.6) .49 0.9 (0.6–1.4) .66 .57

NOTE. No biomarker other than sCD14 was associated with mortality in either treatment arm. CI, confidence interval; EndoCAb, endotoxin core antibody; I-FABP, intestinal fatty acid binding protein; LPS, lipopolysaccharide; OR, odds ratio; rDNA, ribosomal DNA; sCD14, soluble CD14.

a

OR based on univariate analysis derived from conditional logistic model, associated with a one interquartile range higher level of biomarker after log10 transformation.