Table 6.
Correlation of sCD14 and Human Immunodeficiency Virus (HIV) RNA Levels with Inflammatory Markers
IL-6 | Serum amyloid A | hsCRP | D-dimer | ||
HIV RNA level ≤400 copies/mL | sCD14 | r=.18 P<.001 | r=.16 P<.001 | r=.10 P=.04 | r=.11 P=.03 |
HIV RNA level >400 copies/mL | sCD14 | r=.26 P<.001 | r=.18 P=.004 | r=.18 P=.005 | r=.09 P=.16 |
HIV RNA | r=.23 P<.001 | r=.00 P=.93 | r=.04 P=.55 | r=.42 P<.001 |
NOTE. For subjects with HIV RNA ≤ 400 copies/mL, sCD14 levels correlate with levels of the inflammatory markers interleukin (IL)-6, serum amyloid A, C-reactive protein, and D-dimer, a marker of activation of the coagulation pathways, whereas for subjects with HIV RNA >400 copies/mL, sCD14 levels correlate with IL-6, serum amyloid A and CRP. HIV RNA level only correlates with IL-6 and D-dimer. HIV, human immunodeficiency virus; hsCRP, high-sensitivity C-reactive protein; IL, interleukin; sCD14, soluble CD14.