Table 3.
Effects of THA and Silymarin on GSH levels and antioxidant enzyme activities (CAT, SOD, and GPx) in livers of treated mice and of control mice
| Groups | GSH (µmol/mg protein) | CAT (mmol/min/mg protein) | SOD (U SOD/mg protein) | GPx (µmol/min/mg protein) |
|---|---|---|---|---|
| Control group | 34.14±0.12a | 8.31±0.29a | 10.08±0.26a | 33.35±2.00a |
| CCl4 | 24.65±0.14 | 5.33±0.46 | 6.64±0.13 | 23.14±1.80 |
| THA | 30.72±0.18a | 7.87±0.31a | 8.45±0.45a | 34.68±1.10a |
| THA + CCl4 | 31.14±0.14a | 8.17±0.27a | 9.18±0.65a | 29.92±1.30a |
| Silymarin | 32.06±0.22a | 7.70±0.33a | 10.27±0.39a | 32.79±1.42a |
| Silymarin + CCl4 | 29.82±0.15a | 7.43±0.15a | 14.01±0.73a | 31.97±1.50a |
Note: GSH, reduced glutathione; CAT, catalase; SOD, superoxide dismutase; GPx, glutathione peroxidase. Values are mean±SD (n=6).
p<0.01 compared to the CCl4-treated mice.