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. Author manuscript; available in PMC: 2011 Apr 5.
Published in final edited form as: J Am Chem Soc. 2002 Feb 13;124(6):890–891. doi: 10.1021/ja016878n

Figure 1.

Figure 1

Diagram of HH16, the two-strand, 55-nucleotide (nt) hammerhead construct used in this study. Strands of 38 nts (solid) and 17 nts (outline) anneal to form the complete ribozyme. The arrow marks the cleavage site in the active ribozyme. All samples used for CD employed dC at this site to prevent cleavage.