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. 2011 Jan 26;31(4):1170–1182. doi: 10.1523/JNEUROSCI.3539-10.2011

Figure 2.

Figure 2.

Biphasic alterations of excitatory synaptic transmission in D1-YAC128 cells. A, Mean sEPSC frequency and cumulative probability distributions of interevent interval histograms for sEPSCs show that D1-YAC128 cells display higher sEPSC frequencies at 1.5 months, while at 12 months D1-YAC128 cells display lower sEPSC frequencies. B, Mean mEPSC frequency (inset) and cumulative probability distribution of interevent intervals for mEPSCs at 1.5 months show that D1-YAC128 cells display a significantly higher mEPSC frequency. C, PPRs were significantly decreased in D1-YAC128 cells at 1.5 months, indicating increased glutamate release probability. In contrast, PPRs were increased in D1-YAC128 cells at 12 months, indicating decreased probability of glutamate release.