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. 2011 Jan 26;31(4):1170–1182. doi: 10.1523/JNEUROSCI.3539-10.2011

Figure 4.

Figure 4.

Mean amplitude of evoked EPSCs is increased in D2-YAC128 cells at 1.5 months and decreased at 12 months in D1-YAC128 cells. A, Traces show evoked EPSCs in WT (black) and YAC128 (red) at 1.5 and 12 months. Numbers above traces are stimulus intensities. B, Input–output functions show evoked EPSCs at the two ages in WT cells. Currents increase significantly with age in D1 cells but show no change in D2 cells. C, At 1.5 months, evoked EPSC amplitudes are similar in D1-YAC128 compared with D1-WT cells, whereas at 12 months, evoked EPSC amplitudes are decreased in D1-YAC128 cells compared with D1-WT cells. D, At 1.5 months, evoked EPSC amplitudes are increased in D2-YAC128 compared with D2-WT cells while at 12 months, they are similar.