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acrAB mutations detected in end populations. The acrAB locus was sequenced in clonal isolates from each end population (G1, G2, G3, X1, X2, X3). (A) Discovered mutations mapped onto acrA and acrB protein structures, (B) Mutations in acrA and mexB (an acrB homolog in Pseudomonas aerogenosa) associated with changes in substrate specificity or acrA-mexB assembly.
