Summary of RCTs

Author	Number randomized	Population	Interventions	Results
Ozen8	125	Men on AA	RT vs no RT	RT best; P < 0.001
Fradet9	282	Men on AA	tamoxifen (different dosing schedules)	20 mg/day better than smaller doses
Saltzstein10	107	Men on AA	tamoxifen vs anastrozole	tamoxifen better
Perdonà11	51	Men on AA	tamoxifen vs RT	tamoxifen better than RT
Di Lorenzo12	102	Men on AA	tamoxifen vs RT	tamoxifen better than RT
Boccardo13	114	Men on AA	tamoxifen vs anastrozole	tamoxifen better than anastrozole
Tyrrell14	106	Men on AA	RT vs sham RT	RT better; P < 0.001

Abbreviations: AA, anti-androgen drugs; RT, radiotherapy