Table 1.
Emergence of spontaneous seizures following hypoxia-induced neonatal seizures: EEG recordings were performed in rat pups exposed to neonatal seizures and the percentage of pups exhibiting spontaneous recurrent seizures during specified time windows was calculated. The average number of seizures observed during the 3 hour video-EEG recording epoch is tabulated.
| Age Window (postnatal days) | Percentage of animals with spontaneous seizures | Average number of seizures recorded/animal |
|---|---|---|
| P 10–12 (n = 6) | 92% | 4.2 seizures |
| P12–24 (n = 11) | 0% | 0 |
| P25–31 (n = 9) | 21% | 8.3 seizures |
| P32–37 (n = 6) | 50% | 9 seizures |
| P38–58 (n = 9) | 50% | 11.2 seizures |
| P 58 – 180 (n = 11) | 100% | 22 seizures |