Table II.
Elderly and young adult subjects differ in T and NK populations
| Set | Subset | Young | Elderly | Age Effect * |
|---|---|---|---|---|
| Lymphocytes | T | 73.7% | 58.7% | 0.0002 |
| T | TNK | 3.6% | 7.4% | 0.0426 |
| T | TCon | 96.6% | 92.9% | NS |
| T | CD57 | 4.3% | 12.0% | <0.0001 |
| TNK | CD57 | 34.2% | 54.5% | 0.0007 |
| TCon | CD57 | 2.9% | 8.3% | <0.0001 |
| Lymphocytes | NK | 7.4% | 15.9% | <0.0001 |
| NK | CD56bright | 15.4% | 9.1% | 0.0001 |
| NK | CD56dim | 60.7% | 70.5% | 0.0026 |
| NK | CD16−CD56low | 8.1% | 5.0% | 0.0021 |
| NK | CD16+CD56− | 14.8% | 15.3% | NS |
| NK | CD57 | 33.9 | 47.2 | 0.0037 |
| CD56bright | CD57 | 4.2% | 11.4% | 0.0047 |
| CD56dim | CD57 | 47.2% | 57.5% | 0.0261 |
| CD16−CD56low | CD57 | 6.1% | 9.8% | 0.0359 |
| CD16+CD56− | CD57 | 18.2% | 23.3% | NS |
*
Wilcoxon signed-rank test p values; NS, not significant