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. Author manuscript; available in PMC: 2011 Apr 6.
Published in final edited form as: Adv Exp Med Biol. 2008;614:379–386. doi: 10.1007/978-0-387-74911-2_42

Table 1.

Respiratory properties of rat brain mitochondria. Values are mean ± standard deviation.

Age
(mos)		 Condition n State 3
(nO/mg/min)		 State 4
(nO/mg/min)		 RCR ADP/O
Cortex 6 Non-arrested 5 338.4 ± 34.5 29.0 ± 3.0 11.7 ± 1.0 2.1 ± 0.3
6 1 h recovery 3 313.1 ± 16.8 34.9 ± 2* 9.0 ± 0.1* 2.4 ± 0.3
24 Non-arrested 4 317.0 ± 34.4 27.5 ± 2.7 11.5 ± 0.8 2.2 ± 0.3
24 1 h recovery 3 287.8 ± 51.2 34.2 ± 1.3* 8.5 ± 1.0* 2.2 ± 0.1
24 PBN-treated 3 302.5 ± 71.9 28.3 ± 8.8 10.9 ± 1.2 2.5 ± 0.4
Brainstem 6 Non-arrested 5 319.7 ± 40.0 27.4 ± 3.9 11.9 ± 2.2 2.3 ± 0.3
6 1 h recovery 3 297.7 ± 31.7 35.2 ± 1.2* 8.5 ± 0.8* 2.3 ± 0.4
24 Non-arrested 4 248.3 ± 39.0 25.5 ± 2.7 9.7 ± 1.1 2.2 ± 0.1
24 1 h recovery 3 246.8 ± 33.8 35.1 ± 1.3* 7.0 ± 0.8*§ 2.3 ± 0.1
24 PBN-treated 3 278.5 ± 66.4 28.5 ± 4.9 9.7 ± 0.7 2.3 ± 0.2

RCR, respiratory control ratio; ADP/O, ADP-to-oxygen ratio.

*

indicates significant difference (t-test, p<0.05) from the pre-arrest value in the same age group.

§

indicates significant difference (t-test, p<0.05) between the untreated and PBN-treated groups.