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. Author manuscript; available in PMC: 2011 Apr 6.
Published in final edited form as: Clin Breast Cancer. 2010 Jun;10(3):224–229. doi: 10.3816/CBC.2010.n.030

Table 3.

Pearson Correlation Coefficients in Bone Biomarkers and Changes in Cytokines and Growth Factors

Factor Pearson Correlation
Change in BSAP
(Bone Formation)		 P Value Change in NTx
(Bone Resorption)		 P Value Change in Bone
Remodeling Index		 P Value
IGFBP-1 Change −0.54 .05 0.26 .34 −0.43 .14
IGFBP-3 Change −0.10 .75 −0.27 .32 0.19 .53
Cortisol Change −0.36 .23 −0.07 .79 −0.22 .48
IL-2 Change −0.50 .08 −0.05 .84 −0.35 .24
IL-6 Change 0.76 .00 −0.20 .45 0.69 .01
IL-8 Change −0.01 .97 0.23 .39 −0.03 .93

Abbreviations: BSAP = bone-specific alkaline phosphatase; IGFBP = insulin-like growth factor binding protein; IL = interleukin; NTx = N-telopeptides of type I collagen