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. Author manuscript; available in PMC: 2011 Apr 6.
Published in final edited form as: J Inherit Metab Dis. 2010 Feb 12;33(2):113–120. doi: 10.1007/s10545-010-9052-3

Fig. 4.

Fig. 4

a β-Galactosidase activity assay from murine myelinating cocultures. The degree of maturation of oligodendrocytes in the cultures was assessed by quantifying the activation of the myelin basic protein (MBP) promoter through luminometric β-galactosidase activity assay. Results are expressed as relative counts per second (CPS) compared with control condition. b Optical counting of proteolipid protein (PLP)-positive internodes (i.e., myelin sheaths) in murine myelinating cocultures. Results are expressed as ratios of the count from cultures exposed to phenylalanine (Phe) (5 mM), phenylpyruvate (PP) (22 µM), or phenylacetate (PA) (74 µM) to the score from the corresponding control samples. P>0.05 versus control group