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. Author manuscript; available in PMC: 2011 Apr 6.
Published in final edited form as: Kidney Int. 2010 Mar 10;77(11):962–973. doi: 10.1038/ki.2010.40

Figure 4. Glomerular cells are more susceptible to apoptosis in mice with podocyte-specific ablation of c-met.

Figure 4

Immunohistochemical staining reveals the cleaved caspase-3-positive cells in glomeruli. (a–d) Representative micrographs show the cleaved caspase-3-positive glomerular cells in control or podo-met−/− mice after injection with vehicle (a and b) or adriamycin (ADR) (c and d) (25 mg/kg body weight). (e) Quantitative determination of the cleaved caspase-3-positive glomerular cells in different groups as indicated. Data are presented as cleaved caspase-3-positive cells per 100 glomerular cross-sections. *P<0.05 versus vehicle controls, †P<0.05 versus control podo-met +/+ mice after ADR injection (n = 4–8).