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. Author manuscript; available in PMC: 2011 Apr 6.
Published in final edited form as: Kidney Int. 2010 Mar 10;77(11):962–973. doi: 10.1038/ki.2010.40

Figure 6. Hepatocyte growth factor (HGF) prevents glomerular cells from apoptosis induced by adriamycin (ADR).

Figure 6

(a–c) Representative micrographs show the cleaved caspase-3-positive glomerular cells in vehicle controls (a), BALB/c mice injected with ADR and pcDNA3 plasmid (b), and BALB/c mice injected with ADR and pCMV-HGF plasmid (c). Arrow indicates cleaved caspase-3-positive cells. (d) Quantitative determination of the cleaved caspase-3-positive glomerular cells in different groups as indicated. Data are presented as cleaved caspase-3-positive cells per 100 glomerular cross-sections. *P<0.05 versus vehicle controls, †P<0.05 versus pcDNA3 controls (n = 4–11).