Skip to main content
. Author manuscript; available in PMC: 2012 Apr 6.
Published in final edited form as: J Am Chem Soc. 2011 Mar 10;133(13):5152–5159. doi: 10.1021/ja200317w

Table 3.

Effect of proximal guanosines on the ratio of 3′-termini products resulting from strand cleavage by 5,6-dihydrouridin-6-yl (1)

Strand scission (%) Phosphate: Ketone (11)
5′-32P-(GAU CAU AA8U9 2UG UAA UCG C)
3′-(CUA GUA U U A AAC AUU AGC G)
24 		39.6 ± 2.1 6.7 ± 0.1
5′-32P-(GAU CAU AC8U9 2UG UAA UCG C)
3′-(CUA GUA U G A AAC AUU AGC G)
25 		45.7 ± 4.5 3.2 ± 0.8
5′-32P-(GAU CAG GC8U9 2UG CCA UCG C)
3′-(CUA GUC C G A AAC GGU AGC G)
7 		35.2 ± 8.4 5.8 ± 1.2
5′-32P-(GAU CAG GG8U9 2UG UAA UCG C)
3′-(CUA GUC C C A AAC AUU AGC G)
26 		37.1 ± 3.6 4.9 ± 0.7