Table 1. Characteristics of NLCS study participants according to colorectal cancer status after 7.3 years of follow-up.
| MEN | WOMEN | |||||
| Sub-cohort * | CIMP+ | Non-CIMP | Sub-cohort | CIMP+ | Non-CIMP | |
| Baseline characteristics | ||||||
| Total (% of cases) | 2219 | 83 (25) | 245 (75) | 2390 | 81 (30) | 190 (70) |
| Age (years) † | 61.3 (4.2) | 63.0 (4.1) | 62.8 (4.1) | 61.5 (4.3) | 63.3 (4.0) | 62.8 (4.0) |
| Height (cm) | 176.4 (6.7) | 176.5 (6.7) | 176.9 (6.6) | 165.1 (6.2) | 166.5 (6.2) | 166.2 (6.3) |
| BMI (kg/m2) | 25.0 (2.6) | 25.8 (2.6) | 25.3 (2.9) | 25.1 (3.6) | 25.4 (2.9) | 25.6 (3.5) |
| BMI (kg/m2) at age 20 | 21.8 (2.4) | 22.4 (2.5) | 21.8 (2.2) | 21.4 (2.8) | 21.5 (2.2) | 21.6 (2.6) |
| BMI change | ||||||
| Clothing size | 51 (4) | 52 (6) | 52 (3) | 44 (3) | 44(3) | 44(3) |
| Recreational physical activity (%) | ||||||
| <30 min/day | 19 | 21 | 13 | 27 | 33 | 31 |
| 30–60 min/day | 31 | 30 | 32 | 31 | 23 | 32 |
| 60–90 min/day | 18 | 20 | 18 | 22 | 18 | 22 |
| >90 min/day | 31 | 29 | 37 | 21 | 28 | 15 |
| Occupational physical activity (%) | ||||||
| <8 kj/min | 57 | 72 | 63 | 58 | 52 | 51 |
| 8–12 kj/min | 27 | 18 | 22 | 36 | 40 | 40 |
| >12 kj/min | 16 | 11 | 15 | 6 | 8 | 10 |
| Sports participation during youth (%) | ||||||
| Never | 50 | 52 | 49 | 62 | 73 | 62 |
| Only after puberty | 23 | 24 | 20 | 20 | 15 | 22 |
| Before, during, and after puberty | 27 | 24 | 31 | 19 | 12 | 16 |
| Molecular characteristics | ||||||
| Site (%) | ||||||
| Proximal colon | - | 54 | 20 | - | 67 | 25 |
| Distal colon | - | 24 | 39 | - | 18 | 37 |
| Rectosigmoid | - | 5 | 11 | - | 4 | 17 |
| Rectum | - | 17 | 30 | - | 11 | 22 |
| MSI status (%) | ||||||
| Stable | - | 72 | 95 | - | 60 | 97 |
| Unstable | - | 28 | 5 | - | 40 | 3 |
| BRAF V600E mutation status | ||||||
| Wildtype | - | 64 | 94 | - | 54 | 93 |
| Mutated | - | 36 | 6 | - | 46 | 7 |
*from subcohort of 5000 individuals selected randomly at baseline.
†
mean (sd) or percentages where indicated.