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. 2011 Apr 5;6(4):e18467. doi: 10.1371/journal.pone.0018467

Figure 5. Effect of Berberine chloride on MAPK pathway in macrophages.

Figure 5

A: A representative profile of uninfected macrophages was treated with Berberine chloride (10 µM) for 30 min-6 h. The cells were lysed and subjected to Western blotting with anti-pERK1/2 (a), anti-pp38 MAPK (b) and anti-ERK1/2 (c) as described in Methods. B: A representative profile of Leishmania infected macrophages were treated with Berberine chloride (10 µM) for 30 min-6 h. The cells were lysed and subjected to western blotting with anti-pERK1/2 (a), anti-pp38 MAPK (b) and anti-ERK1/2 (c) as described in Methods.