Table 2. The frequencies of the β2-adrenergic receptor gene C-47T, A46G and C79G polymorphisms genotypes.
Genotype (frequency,%) | P* | Allele (frequency,%) | P** | |||||
C-47T | TT | CT | CC | T allele | C allele | |||
Case (Total) | 571(77.2) | 163(22.0) | 6(0.8) | 1305(88.2) | 175(11.8) | |||
Control (Total) | 314(80.7) | 68(17.5) | 7(1.8) | 0.358 | 696(89.5) | 82(10.5) | 0.361 | |
Case (Male) | 371(78.3) | 100(21.1) | 3(0.6) | 842(88.8) | 106(11.2) | |||
Control (Male) | 187(80.6) | 41(17.7) | 4(1.7) | 0.723 | 415(89.4) | 49(10.6) | 0.726 | |
Case (Female) | 200(75.2) | 63(23.7) | 3(1.1) | 463(87.0) | 69(13.0) | |||
Control (Female) | 127(80.9) | 27(17.2) | 3(1.9) | 0.289 | 281(89.5) | 33(10.5) | 0.288 | |
A46G | AA | AG | GG | A allele | G allele | |||
Case (Total) | 208(28.3) | 369(50.2) | 158(21.5) | 785(53.4) | 685(46.6) | |||
Control (Total) | 143(37.3) | 174(45.4) | 66(17.2) | 0.003 | 460(60.1) | 306(39.9) | 0.003 | |
Case (Male) | 135(28.8) | 239(51.0) | 95(20.3) | 509(54.3) | 429(45.7) | |||
Control (Male) | 94(40.9) | 98(42.6) | 38(16.5) | 0.006 | 286(62.2) | 174(37.8) | 0.005 | |
Case (Female) | 73(27.4) | 130(48.9) | 63(23.7) | 276(51.9) | 256(48.1) | |||
Control (Female) | 49(32.0) | 76(49.7) | 28(18.3) | 0.167 | 174(56.9) | 132(43.1) | 0.164 | |
C79G | CC | CG | GG | C allele | G allele | |||
Case (Total) | 566(76.8) | 164(22.3) | 7(0.9) | 1296(87.9) | 178(12.1) | |||
Control (Total) | 301(80.5) | 66(17.6) | 7(1.9) | 0.335 | 668(89.3) | 80(10.7) | 0.337 | |
Case (Male) | 367(77.9) | 100(21.2) | 4(0.8) | 834(88.5) | 108(11.5) | |||
Control (Male) | 185(80.4) | 41(17.8) | 4(1.7) | 0.649 | 411(89.3) | 49(10.7) | 0.650 | |
Case (Female) | 199(74.8) | 64(24.1) | 3(1.1) | 462(86.8) | 70(13.2) | |||
Control (Female) | 116(80.6) | 25(17.4) | 3(2.1) | 0.319 | 257(89.2) | 31(10.8) | 0.319 |
*P value of the comparison of the additive genetic model using the generalized linear model.
**P value of the comparison of allelic frequencies.