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. 2011 Apr 6;6(4):e18688. doi: 10.1371/journal.pone.0018688

Table 1. SIV-infected, CD8+ T Lymphocyte depleted animals used in this study.

Animal no. Minocycline Length of infection (days) CD8+ lymphocyte depletiona Terminal plasma viral load (copy eq. /mL)b
74 – 05 None 56 Persistently depleted 5.6×107
79 - 05 None 42* Persistently depleted 6.3×107
156 - 04 None 62 Persistently depleted 3.6×108
346 - 04 None 62 Persistently depleted 6.2×108
307 - 05 None 43* Persistently depleted 6.5×107
118 - 07 None 57 Persistently depleted 1.8×108
121 - 07 None 57 Persistently depleted 2.2×108
94 - 04 Started 28 dpi 60 Persistently depleted 9.0×106
35 - 07 Started 28 dpi 62 Persistently depleted 8.0×107
150 - 04 Started 28 dpi 60 Persistently depleted 8.3×107
150 - 05 Started 28 dpi 55 Persistently depleted 6.3×107
48 - 07 Started 28 dpi 62 Transiently depleted 4.3×106
227 - 04 Started 28 dpi 60 Transiently depleted 8.9×106
258 - 04 Started 28 dpi 62 Transiently depleted 2.7×107

Note.-dpi = days post infection.

*Untreated animals time-sacrificed at 6 weeks pi; all other animals sacrificed at 8 weeks pi.

a

Transiently CD8+ lymphocyte depleted (≤21 dpi), persistently CD8+ lymphocyte depleted (>28 dpi).

b

Viral RNA quantitiated using RT PCR and are results of duplicate measurements.