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Cause of tocilizumab discontinuation
| Cause of discontinuation | Number of cases/events |
|---|---|
| Lack of efficacy | 12 cases (5.2%) |
| Adverse events | 26 cases (11.4%) |
| Pneumonia | 6 |
| Heart failure | 3 |
| Worsening comorbidity | 3 |
| Liver damage | 2 |
| Interstitial pneumonia | 2 |
| Skin ulcer | 2 |
| Cerebellar hemorrhage | 2 |
| Anaphylaxis | 1 |
| Chest pain | 1 |
| Myocardial infarction | 1 |
| Leukopenia | 1 |
| Breast cancer | 1 |
| Phlegmon | 1 |
| Miscellaneous | 9 cases (3.9%) |
| Unknown | 4 |
| Moving | 3 |
| Patient’s will | 2 |
| Total | 47 cases (20.5%) |
