Table 1.

Plasma hormone and glucose levels and glucose infusion rate during morning and afternoon glucose clamps

Measurement	Euglycaemia		Hypoglycaemia
	Morning	Afternoon	Morning	Afternoon
Glucose (mmol/l)	4.9 (0.1)	4.7 (0.1)	2.9 (0.1)a	2.9 (0.0)a
GIR (μmol kg-1 min-1)	38.1 (1.1)	43.8 (1.2)	9.4 (1.7)a	6.9 (1.6)a
Insulin (pmol/l)	547 (28)	580 (47)	524 (40)	564 (60)
Glucagon (pmol/l)	22.4 (0.9)	20.1 (0.6)	47.4 (5.6)a	32.8(3.5)ab
Cortisol (μmol/l)	0.32 (0.03)	0.27 (0.04)	0.65 (0.04)a	0.63 (0.05)a
Adrenaline (nmol/l)	0.18 (0.02)	0.20 (0.04)	2.93 (0.40)a	2.62 (0.27)a
Noradrenaline (nmol/l)	1.37 (0.14)	1.32 (0.15)	1.64 (0.78)	1.78 (0.19)

Values are means (SEM)

GIR, glucose infusion rate

^a p < 0.05 compared with euglycaemia; ^b p < 0.05 compared with morning experiment