Table II.

The effect of the senna extract on the biodistribution of Na^99mTcO₄ in Wistar rats.

Organs	Control (%ATI/g)	Treated (%ATI/g)
Blood	1.37±0.23	0.90±0.24**
Bone	0.39±0.13	0.31±0.10
Brain	0.07±0.02	0.06±0.02
Duodenum	1.01±0.26	0.81±0.29
Heart	0.48±0.14	0.38±0.15
Kidney	0.66±0.15	0.65±0.12
Large intestine	0.40±0.16	0.39±0.06
Liver	0.79±0.13	0.60±0.12*
Lungs	0.89±0.14	0.69±0.10*
Muscle	0.17±0.02	0.16±0.02
Pancreas	0.62±0.23	0.39±0.09*
Spleen	0.51±0.11	0.47±0.09
Stomach	2.44±1.08	2.19±1.10
Testes	0.20±0.04	0.19±0.05
Thyroid	5.64±2.27	3.16±1.50*

Male Wistar rats were treated with an aqueous senna extract that was intragastrically administered daily. After seven days, Na^99mTcO₄ (3.7 MBq) was administered and the animals were sacrificed. The animals' organs were isolated, the mass of each organ was determined and the percentage of radioactivity per gram of each organ (%ATI/gram) was calculated (1 mL of blood was considered to weigh 1 g). Animals in the control group were treated with saline (0.9% NaCl). (*) p<0.05, (**) p<0.01 when compared with the control group.