. Author manuscript; available in PMC: 2011 Sep 17.

Published in final edited form as: Nature. 2011 Mar 2;471(7338):373–376. doi: 10.1038/nature09878

Table 1. Genetic analysis of FADD and RIP1 deficiency in mice.

Timed pregnancy analyses were set up to determine the frequencies of each genotype of offspring from intercrosses of FADD^+/−RIP1^+/− mice. The actual (shaded) and expected numbers of each or groups of genotypes were shown. Neonates were sacrificed and analyzed at birth (0 day) or monitored for survival for up to 6 month (>0 days). Numbers of DKO embryos or neonates were in bold. Postnatal RIP1^−/− and DKO neonates (>0 days) died within 4 days after birth.

Genotype		FADD	+/+ or +/−	+/+ or +/−	−/−	−/−	Total

		RIP1	+/+ or +/−	−/−	+/+ or +/−	−/−
E14.5-18.5 embryos		Actual	102	45	17	14	178
E14.5-18.5 embryos		Expected	100	33	33	11

At or after birth	Day 0	Actual	26	4	0	1	31
	Day 0	Expected	17	6	6	2

	>day 0	Actual	79	19	0	6	104
	>day 0	Expected	59	20	20	7