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. 2010 Oct 9;82(5):569–573. doi: 10.1136/jnnp.2010.217489

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© 2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

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Power autospectra of local field potential (LFP) recorded between contacts 1 and 3 from left subthalamic nucleus deep brain stimulation (DBS) electrode in case 1. Log power autospectra show a peak centred at 8.6 Hz (left vertical arrow), which is unaffected by amplifier type or DBS applied to contact 2 (pulse-width 60 μs; frequency 130 Hz), and a peak centred around 25 Hz (right vertical arrow), which is unaffected by amplifier type but which is suppressed by DBS applied to contact 2 at 2.5 V (130 Hz). The latter was also the threshold for the suppression of contralateral rigidity and bradykinesia as determined by clinical examination using stimulation of the same contact pair performed at a different time on the same day. Two kinds of amplifier were used: Digitimer D360 and our custom-built amplifier. Frequency resolution is 1 Hz. Autospectra averaged over 110 s recorded during same experimental session, but not simultaneously.