Table 3.
Dog specific IgE levels and prediction of any symptom when exposed to dogs
| IgE Cutoff (kU/L) |
Sensitivity Rate (95% CI) |
Specificity Rate (95% CI) |
Sum of Sensitivity + Specificity |
PPV | NPV | Percent Misclassified |
|---|---|---|---|---|---|---|
| Teen Sample (N=564) | ||||||
| 0.20 | 56.1 (44.7-67.0) |
79.5 (75.6-83.0) |
135.6 | 31.7 (24.3-40.0) |
91.4 (88.3-93.9) |
23.9 (20.5-27.7) |
| 0.35 | 41.5 (30.7-52.9) |
86.1 (82.7-89.1) |
127.6 | 33.7 (24.6-43.8) |
89.6 (86.5-92.3) |
20.4 (17.1-24.0) |
| ** | ** | |||||
| Mothers (N=470) | ||||||
| 0.20 | 46.6 (33.3-60.1) |
87.6 (84.0-90.6) |
134.2 | 34.6 (24.2-46.2) |
92.1 (89.0-94.6) |
17.4 (14.1-21.2) |
| 0.35 | 39.7 (27.0-53.4) |
93.0 (90.0-95.2) |
132.7 | 44.2 (30.5-58.7) |
91.6 (88.5-94.1) |
13.6 (10.6-17.1) |
| * | ** | |||||
| Fathers (N=346) | ||||||
| 0.20 | 53.6 (33.9-72.5) |
84.3 (79.8-88.1) |
137.9 | 23.1 (13.5-35.2) |
95.4 (92.2-97.5) |
18.2 (14.3-22.7) |
| 0.35 | 50.0 (30.6-69.4) |
89.0 (85.0-92.2) |
139 | 28.6 (16.6-43.3) |
95.3 (92.2-97.4) |
14.2 (10.7-18.3) |
| p = 0.32 | ** | |||||
*
p<0.05 in comparing 0.20vkU/L to 0.35kU/L sIgE levels
**
p<0.01 comparing 0.20 kU/L to 0.35kU/L sIgE levels