Fig. 6.

Representative example of intracranial U87dEGFR-mCherry glioblastoma reconstruction. (a) A 3D view of the surface of the mouse’s head, sources (red crosses) and detectors (blue circles) are projected on the surface. The black rectangle indicates the position of the axial slice 3. (b) A fluorescence epi-illumination image of histological section (slice #3) of the brain, blue – reflectance image at 593 nm, magenta – mCherry fluorescence emission at 620 nm when excited at 593 nm. (c) Single- and multi-spectral reconstructions of the mCherry fluorescence at the axial slice #3. (d) A series of axial slices of the mCherry tumor reconstructed fluorescence, and (e) Corresponding post-Gd-DTPA enhanced axial slices from the T₁-weighted MRI series. Orange arrows indicate the position of the glioma. Colorbar for 
(c) and (d) is in arbitrary units. Dashed lines in (c) and (d) are visual guides to indicate the brain area.