Table 3.
Technique | Lid Region | Grading Scheme | Reference |
---|---|---|---|
Meiboscopy | LL | 0 = no dropout | Pflugfelder et al.55 |
1 = ≤33% | |||
2 = 34%–66% | |||
3 = ≥67 | |||
Percent of partial or total gland dropout | |||
Separate measurement over the nasal and temporal halves of the lower lid | |||
Meibography (contact; retro-illumination) | LL | Total number of glands lost of eight central of the lower lid. Half gland loss was given a grade of 0.5 | Mathers et al.96,97 |
1 = normal | Jester et al.105 | ||
2 = gland visible w/decreased absorption | |||
3 = acini atrophic; duct visible | |||
4 = no structures visible | |||
LL | 0 = no dropout | Shimazaki et al.86,87 | |
1 = ≤50% dropout | |||
2 = ≥51% dropout | |||
LL | Dropout: (nasal half, lower eyelid) | de Paiva et al.106 | |
0 = no dropout | Composite score with lids signs and expressibility (0–11) | ||
1 = ≤25% | |||
2 = ≤50% | |||
3 = ≤75% | |||
4 = ≤100% | |||
LL ≅ 15 glands | Gestalt method: | Nichols et al.107 | |
1 = no partial glands (PGs) | |||
2 = <25% PGs | |||
3 = 25%–75% PGs | |||
4 = >75% PGs | |||
Noncontact | LL and UL | 0 = no loss, | Arita et al.3 |
1 = gland loss <33% of total area | |||
2 = loss, 33%–67% | |||
3 = >67% loss | |||
Scores of upper and lower lid summed | |||
Scale range 0–6 | |||
Confocal microscopy | LL and/or UL | Acinar density: number of glands//mm2 (based on a 400 × 400 micrometer field) mean acinar diameter | Matsumoto et al.79 |
LL, lower lid; UL, upper lid.