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. 2010 Nov 9;3(2):180–199. doi: 10.1159/000321157

Fig. 6.

Fig. 6

Fig. 6

Fig. 6

Fig. 6

Liver-specific cellular immune response in a fatal mouse model of systemic IC. Inoculum, 2.5 × 105 CFU. a Representative 7/4+ IHC images from liver cross-sections at different time points after infection. Original magnifications: ×20 (top row) and ×400 (bottom row). Brown color represents 7/4+ immune cells. b Representative PAS staining of the liver at different time points after infection. Original magnification: ×400. Arrows point to Candida yeast and germ tube forms. c Representative FACS plots of neutrophils and inflammatory monocytes in the liver at different time points after infection and in the uninfected state. Graphs show neutrophils, monocytes and macrophages as percent of CD45+ cells, and as absolute numbers per liver or per gram of tissue. d Accumulation of NK1.1+ cells, T and B lymphocytes, and dendritic cells in the liver after Candida challenge. Data are from a single FACS experiment with 3 mice per time point. Graphed are the mean ± SEM data.

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